For research use only. Not for therapeutic Use.
EHNA hydrochloride(Cat No.:R004066)(erythro-9-(2-hydroxy-3-nonyl)adenine hydrochloride) is a selective inhibitor of adenosine deaminase (ADA), an enzyme that catalyzes the deamination of adenosine to inosine. By inhibiting ADA, EHNA hydrochloride increases adenosine levels, which modulates various physiological processes, including vasodilation and immune responses. Additionally, EHNA inhibits phosphodiesterase 2 (PDE2), making it useful in cardiovascular and neurological research. Its dual inhibitory action has made EHNA hydrochloride a valuable tool in studying adenosine-mediated pathways, with applications in inflammation, cardiac function, and neuroprotection studies.
Catalog Number | R004066 |
CAS Number | 58337-38-5 |
Synonyms | EHNA HCl; (αR,βS)-rel-6-Amino-β-hexyl-α-methyl-9H-purine-9-ethanol Hydrochloride Salt; NSC 263164 Hydrochloride Salt |
Molecular Formula | C₁₄H₂₃N₅O ∙ HCl |
Purity | ≥95% |
Storage | -20°C |
IUPAC Name | (2R,3S)-3-(6-aminopurin-9-yl)nonan-2-ol;hydrochloride |
InChI | InChI=1S/C14H23N5O.ClH/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19;/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17);1H/t10-,11+;/m1./s1 |
InChIKey | VVDXNJRUNJMYOZ-DHXVBOOMSA-N |
SMILES | CCCCCC[C@@H]([C@@H](C)O)N1C=NC2=C(N=CN=C21)N.Cl |