For research use only. Not for therapeutic Use.
5(Z),14(Z)-<wbr></wbr>Eicosadienoic Acid is a novel ω-<wbr></wbr>6 C20:2 fatty acid. The more common 11(Z),14(Z)-<wbr></wbr>eicosadienoic acid competitively inhibits inosine 5’-<wbr></wbr>monophosphate dehydrogenase (K<sub>i</sub> = 3.1 µM) and inhibits the binding of LTB<sub>4</sub> to its receptor on neutrophils (K<sub>i</sub> = 3.0 µM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance. Eicosadienoic acids are converted by desaturases, <em>in vivo</em>, to eicosatrienoic acids, which are potent vasodilators. The physiological effects of 5(Z),14(Z)-<wbr></wbr>eicosadienoic acid are unstudied.
| Catalog Number | M136862 |
| CAS Number | 122055-58-7 |
| Synonyms | 5Z,14Z-eicosadienoic acid |
| Molecular Formula | C20H36O2 |
| Purity | ≥95% |
| Storage | -20°C |
| InChIKey | ZPYAEYLYGOTGGC-OYAITDOQSA-N |
