EIDD-1931

• CAT Number: I026767
• CAS Number: 3258-02-4
• Molecular Formula: C9H13N3O6
• Molecular Weight: 259.218
• Purity: 98%
• Synonyms: EIDD-1931; EIDD 1931; EIDD1931; N4-Hydroxycytidine; β-D-N4-hydroxycytidine; Uridine, 4-oxime; NHC; EIDD-2801-metabolite; Molnupiravir-,etabolite
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: N4-Hydroxycytidine
• InChI: InChI=1S/C9H13N3O6/c13-3-4-6(14)7(15)8(18-4)12-2-1-5(11-17)10-9(12)16/h1-2,4,6-8,13-15,17H,3H2,(H,10,11,16)/t4-,6-,7-,8-/m1/s1
• InChIKey: XCUAIINAJCDIPM-XVFCMESISA-N
• SMILES: OC[C@@H]1[C@H]([C@H]([C@H](N2C(N=C(C=C2)NO)=O)O1)O)O

EIDD-1931 (Cat. No: I026767), an active metabolite of EIDD-2801, is a promising COVID-19 inhibitor. The average IC₅₀ value of EIDD-1931 (NHC) against SAChemicalbookRS-CoV-2, MERS-CoV, SARS-CoV, and relatedzoonoticgroup2b or2cBat-CoVs was 0.15μM, and the efficacy of EIDD-1931 against coronavirus with resistance mutation to nucleoside analogue inhibitor Remdesivir was enhanced.

Reference

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