EJMC-1

• CAT Number: I043528
• CAS Number: 397281-20-8
• Molecular Formula: C17H11ClN2O4S
• Molecular Weight: 374.80
• Purity: ≥95%
• Synonyms: N-(3-chloro-4-hydroxyphenyl)-2-oxo-1H-benzo[cd]indole-6-sulfonamide
• InChI: InChI=1S/C17H11ClN2O4S/c18-12-8-9(4-6-14(12)21)20-25(23,24)15-7-5-13-16-10(15)2-1-3-11(16)17(22)19-13/h1-8,20-21H,(H,19,22)
• InChIKey: FQWAQUPLBBOCSP-UHFFFAOYSA-N
• SMILES: C1=CC2=C(C=CC3=C2C(=C1)C(=O)N3)S(=O)(=O)NC4=CC(=C(C=C4)O)Cl

EJMC-1 is a moderately potent TNF-α inhibitor with an IC50 value of 42 μM[1].

Reference

[1]. Deng X, et al. Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors. Front Chem. 2018 Apr 4;6:98.
 [Content Brief]