Elaidic Acid

• CAT Number: R061608
• CAS Number: 112-79-8
• Molecular Formula: C18H34O2
• Molecular Weight: 282.468
• Purity: ≥95%
• Synonyms: (9E)-Octadecenoic acid; (E)-9-Octadecenoic acid; (E)-Oleic acid; 9-trans-Octadecenoic acid; 9-trans-Oleic acid; Elaidinic acid; NSC 26988; trans-9-Octadecenoic acid; trans-Elaidic acid; trans-Oleic acid; trans-Δ9-Octadecenoic acid; Δ9-trans-Octadecen
• Target: Endogenous Metabolite
• Storage: -20°C
• IUPAC Name: (E)-octadec-9-enoic acid
• InChI: InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9+
• InChIKey: ZQPPMHVWECSIRJ-MDZDMXLPSA-N
• SMILES: CCCCCCCCC=CCCCCCCCC(=O)O

Elaidic acid is the 9-<wbr></wbr>trans isomer of oleic acid. It is a monounsaturated trans-<wbr></wbr>fatty acid which can be found in partially hydrogenated cooking oils. In human platelets incubated with arachidonic acid, elaidic acid inhibits HHT and HETE formation while inducing prostaglandin and thromboxane synthesis.

Reference

1. M. Abbey and P. Nestel “Plasma cholesteryl ester transfer protein activity is increased when trans-elaidic acid is substituted for cis-oleic acid in the diet”Atherosclerosis, Vol. 106(1) pp. 99-107, 19942. M. Ruth et al. “Vaccenic and Elaidic Acid Modify Plasma and Splenocyte Membrane Phospholipids and Mitogen-Stimulated Cytokine Production inObese Insulin Resistant JCR: LA-cp Rats” Nutrients, Vol. 2 pp. 181-197, 20103. P. Nestel et al. “Plasma lipoprotein lipid and Lp(a) changes with substitution of elaidic acid for oleic acid in the diet” Journal of Lipid Research, Vol. 33pp. 1029-1036, 19924. M. Williams et al. “Risk of Preeclampsia in Relation to Elaidic Acid (Trans Fatty Acid) in Maternal Erythrocytes” Gynecologic and ObstetricInvestigation, Vol. 46(2), 1998