Elamipretide

• CAT Number: I004736
• CAS Number: 736992-21-5
• Molecular Formula: C32H49N9O5
• Molecular Weight: 639.79
• Purity: ≥95%
• Synonyms: bendavia
• Target: cardiolipin peroxidase inhibitor
• Solubility: DMSO ≥ 29 mg/mL
• Storage: -20°C
• IUPAC Name: (2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]hexanamide
• InChI: InChI=1S/C32H49N9O5/c1-19-15-22(42)16-20(2)23(19)18-27(41-29(44)24(34)11-8-14-38-32(36)37)31(46)39-25(12-6-7-13-33)30(45)40-26(28(35)43)17-21-9-4-3-5-10-21/h3-5,9-10,15-16,24-27,42H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,43)(H,39,46)(H,40,45)(H,41,44)(H4,36,37,38)/t24-,25+,26+,27+/m1/s1
• InChIKey: SFVLTCAESLKEHH-WKAQUBQDSA-N
• SMILES: CC1=CC(=CC(=C1CC(C(=O)NC(CCCCN)C(=O)NC(CC2=CC=CC=C2)C(=O)N)NC(=O)C(CCCN=C(N)N)N)C)O

Elamipretide（Cat No.:I004736）is a novel mitochondrial-targeted peptide designed to enhance cellular energy production by optimizing mitochondrial function. This compound primarily interacts with cardiolipin, a crucial lipid in the mitochondrial inner membrane, helping to stabilize its structure and improve electron transport chain efficiency. Elamipretide has shown promise in clinical trials for treating conditions linked to mitochondrial dysfunction, including age-related macular degeneration, heart failure, and rare mitochondrial diseases. Its ability to potentially reverse mitochondrial decay makes it a significant candidate in the pursuit of therapies for chronic and degenerative diseases.