Elimusertib (BAY-1895344) hydrochloride

• CAT Number: I047257
• Molecular Formula: C20H22ClN7O
• Molecular Weight: 411.89
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: CC1COCCN1C2=NC3=C(C=CN=C3C4=CC=NN4)C(=C2)C5=CC=NN5C

Elimusertib (BAY-1895344) hydrochloride is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.

Reference

[1] Ulrich T. Luecking, et al. AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 983.
[2] Antje Margret Wengner, et al. AACR; Cancer Res 2017. 77(13 Suppl):Abstract nr 836.
[3] Tang Z, et al. Clin Cancer Res. 2021 Sep 1;27(17):4898-4909.