For research use only. Not for therapeutic Use.
Ellipticine Hydrochloride(CAT: I020685) is a potent DNA-intercalating agent and topoisomerase II inhibitor extensively used in cancer research. Known for its ability to induce apoptosis and inhibit tumor cell proliferation, it is widely studied for its anticancer properties. Ellipticine Hydrochloride’s mechanism involves binding to DNA, interfering with replication and transcription processes, and promoting oxidative DNA damage through cytochrome P450-mediated metabolism. Its versatility makes it an essential tool for exploring the molecular pathways of cancer progression and evaluating novel therapeutic strategies. This compound is also valuable in studying drug-DNA interactions and chemotherapeutic resistance mechanisms.
| Catalog Number | I020685 |
| CAS Number | 5081-48-1 |
| Molecular Formula | C₁₇H₁₅ClN₂ |
| Purity | ≥95% |
| Target | Topoisomerase |
| IUPAC Name | 5,11-dimethyl-6H-pyrido[4,3-b]carbazole;hydrochloride |
| InChI | InChI=1S/C17H14N2.ClH/c1-10-14-9-18-8-7-12(14)11(2)17-16(10)13-5-3-4-6-15(13)19-17;/h3-9,19H,1-2H3;1H |
| InChIKey | VSBNVARERCGCEF-UHFFFAOYSA-N |
| SMILES | CC1=C2C=CN=CC2=C(C3=C1NC4=CC=CC=C43)C.Cl |
