For research use only. Not for therapeutic Use.
ELOVL1-IN-2 is an elongation of very long chain fatty acid 1 (ELOVL1) enzyme inhibitor, ELOVL1-IN-2 shows weak ELOVL1 inhibition (IC50=21 μM) and moderate potency in a primary cellular assay (HEK293 C26 IC50=6.7 μM) [1].
| Catalog Number | I044018 |
| CAS Number | 2761063-79-8 |
| Synonyms | 2-[2-(4-fluorophenyl)ethoxy]-5-pyridin-3-ylpyridine |
| Molecular Formula | C18H15FN2O |
| Purity | ≥95% |
| InChI | InChI=1S/C18H15FN2O/c19-17-6-3-14(4-7-17)9-11-22-18-8-5-16(13-21-18)15-2-1-10-20-12-15/h1-8,10,12-13H,9,11H2 |
| InChIKey | ORFSLMVMPYSSHX-UHFFFAOYSA-N |
| SMILES | C1=CC(=CN=C1)C2=CN=C(C=C2)OCCC3=CC=C(C=C3)F |
| Reference | [1]. Boyd MJ, Collier PN, Clark MP, et al. Discovery of Novel, Orally Bioavailable Pyrimidine Ether-Based Inhibitors of ELOVL1. J Med Chem. 2021;64(24):17777-17794. |
