For research use only. Not for therapeutic Use.
ELQ-300(Cat No.:M015351)is a potent antimalarial compound known for its efficacy against both liver and blood-stage Plasmodium parasites. As an inhibitor of the mitochondrial cytochrome bc1 complex, ELQ-300 disrupts the parasite’s energy metabolism, making it a valuable tool in combating malaria. Its unique mechanism of action helps address drug-resistant strains of Plasmodium, offering potential as part of combination therapies. With a long half-life and strong activity at low doses, ELQ-300 is an important candidate in the development of next-generation antimalarial treatments.
Catalog Number | M015351 |
CAS Number | 1354745-52-0 |
Synonyms | ELQ-300 |
Molecular Formula | C24H17ClF3NO4 |
Purity | ≥95% |
Storage | -20°C |
IUPAC Name | 6-chloro-7-methoxy-2-methyl-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]-1H-quinolin-4-one |
InChI | InChI=1S/C24H17ClF3NO4/c1-13-22(23(30)18-11-19(25)21(31-2)12-20(18)29-13)14-3-5-15(6-4-14)32-16-7-9-17(10-8-16)33-24(26,27)28/h3-12H,1-2H3,(H,29,30) |
InChIKey | WZDNKHCQIZRDKW-UHFFFAOYSA-N |
SMILES | CC1=C(C(=O)C2=CC(=C(C=C2N1)OC)Cl)C3=CC=C(C=C3)OC4=CC=C(C=C4)OC(F)(F)F |