ELQ-300

For research use only. Not for therapeutic Use.

  • CAT Number: M015351
  • CAS Number: 1354745-52-0
  • Molecular Formula: C24H17ClF3NO4
  • Molecular Weight: 475.85
  • Purity: ≥95%
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ELQ-300(Cat No.:M015351)is a potent antimalarial compound known for its efficacy against both liver and blood-stage Plasmodium parasites. As an inhibitor of the mitochondrial cytochrome bc1 complex, ELQ-300 disrupts the parasite’s energy metabolism, making it a valuable tool in combating malaria. Its unique mechanism of action helps address drug-resistant strains of Plasmodium, offering potential as part of combination therapies. With a long half-life and strong activity at low doses, ELQ-300 is an important candidate in the development of next-generation antimalarial treatments.


Catalog Number M015351
CAS Number 1354745-52-0
Synonyms

ELQ-300

Molecular Formula C24H17ClF3NO4
Purity ≥95%
Storage -20°C
IUPAC Name 6-chloro-7-methoxy-2-methyl-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]-1H-quinolin-4-one
InChI InChI=1S/C24H17ClF3NO4/c1-13-22(23(30)18-11-19(25)21(31-2)12-20(18)29-13)14-3-5-15(6-4-14)32-16-7-9-17(10-8-16)33-24(26,27)28/h3-12H,1-2H3,(H,29,30)
InChIKey WZDNKHCQIZRDKW-UHFFFAOYSA-N
SMILES CC1=C(C(=O)C2=CC(=C(C=C2N1)OC)Cl)C3=CC=C(C=C3)OC4=CC=C(C=C4)OC(F)(F)F

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