Elsinochrome A

• CAT Number: I026798
• CAS Number: 24568-67-0
• Molecular Formula: C30H24O10
• Molecular Weight: 544.51
• Purity: 98%
• Synonyms: Elsinochrome A; Elsinochrome-A; NSC 623609; NSC623609; NSC-623609
• Target: NF-κB
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
• IUPAC Name: 12,13-diacetyl-9,16-dihydroxy-5,10,15,20-tetramethoxyhexacyclo[12.8.0.02,11.03,8.04,21.017,22]docosa-1(14),2(11),3(8),4(21),5,9,15,17(22),19-nonaene-7,18-dione
• InChI: InChI=1S/C30H24O10/c1-9(31)15-16(10(2)32)26-24-22-18(28(36)30(26)40-6)12(34)8-14(38-4)20(22)19-13(37-3)7-11(33)17-21(19)23(24)25(15)29(39-5)27(17)35/h7-8,15-16,33-34H,1-6H3/t15-,16-/m1/s1
• InChIKey: WTZSLZBEQHGTRK-HZPDHXFCSA-N
• SMILES: CC([C@H]1C(C2=C(C3=C4C(OC)=CC(O)=C5C4=C2C([C@@H]1C(C)=O)=C(C5=O)OC)C6=C(O)C=C3OC)=C(C6=O)OC)=O

Elsinochrome A (Cat.No:I026798) is a perylenequinone fungal metabolite that has been found in Hypomyces and has anticancer activity. Photoactivation of elsinochrome A induces the production of singlet oxygen and apoptosis in R366.4 rhesus monkey embryonic stem cells and HCe-8693 colorectal carcinoma cells when used at concentrations ranging from 1 to 100 µM.

Reference

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