For research use only. Not for therapeutic Use.
Emodinanthrone, an anthraquinone, is a sprecursor of Emodin (HY-14393) with antibiotic activity. Emodinanthrone inhibits respiration-driven solute transport at micromolar concentrations in membrane vesicles of Escherichia coli[1][2][3].
Emodinanthrone is used as an alternative substrate for the AknX oxygenase assay[1].
| Catalog Number | I044792 |
| CAS Number | 491-60-1 |
| Synonyms | 1,3,8-trihydroxy-6-methyl-10H-anthracen-9-one |
| Molecular Formula | C15H12O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H12O4/c1-7-2-8-4-9-5-10(16)6-12(18)14(9)15(19)13(8)11(17)3-7/h2-3,5-6,16-18H,4H2,1H3 |
| InChIKey | LAJSXCAVRQXZIO-UHFFFAOYSA-N |
| SMILES | CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2)C=C(C=C3O)O |
| Reference | [1]. Jin-Young Chung, et al. Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus. J Bacteriol. 2002 Nov;184(22):6115-22. [2]. T Ubbink-Kok, et al. Inhibition of electron transfer and uncoupling effects by emodin and emodinanthrone in Escherichia coli. Antimicrob Agents Chemother. 1986 Jul;30(1):147-51. [3]. M K Wang, et al. Triterpenoid saponins from Berneuxia thebetica. Phytochemistry. 1998 Aug;48(8):1411-4. |
