Emtricitabine 5'-triphosphate

• CAT Number: M097632
• CAS Number: 145819-92-7
• Molecular Formula: C8H13FN3O12P3S
• Molecular Weight: 487.18
• Purity: ≥95%
• Synonyms: Triphosphoric acid, P-[[5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl] ester, (2R-cis)-; 1,3-Oxathiolane, triphosphoric acid deriv.; Emtricitabine 5′-triphosphate; Emtricitabine triphosphate
• Target: HIV
• Storage: -20°C

Emtricitabine 5′-triphosphate（Cat No.:M097632） is the active triphosphate metabolite of Emtricitabine, a nucleoside reverse transcriptase inhibitor (NRTI) widely used in antiretroviral therapy for HIV-1 infection. As a triphosphate form, it mimics the natural substrates of the viral reverse transcriptase enzyme, incorporating itself into the viral DNA during replication and leading to premature chain termination. This action effectively halts the replication process of the virus. Its high affinity and specificity for the reverse transcriptase enzyme make it a crucial component in HIV treatment regimens, often combined with other antiretrovirals to enhance efficacy and reduce resistance.