For research use only. Not for therapeutic Use.
Emtricitabine(Cat No.:A000770)is a nucleoside reverse transcriptase inhibitor (NRTI) used in the treatment and prevention of HIV infection. It works by inhibiting the reverse transcriptase enzyme, preventing the virus from replicating its genetic material and thus reducing viral load in the body. Emtricitabine is commonly used in combination with other antiretroviral drugs for a more effective therapy. It is also a key component of pre-exposure prophylaxis (PrEP) to prevent HIV infection in high-risk individuals. Well-tolerated, common side effects include headaches, diarrhea, and skin discoloration. Emtricitabine is crucial in managing and preventing HIV/AIDS.
Catalog Number | A000770 |
CAS Number | 143491-57-0 |
Synonyms | 143491-57-0; Emtriva; Coviracil; Racivir; (-)-FTC |
Molecular Formula | C8H10FN3O3S |
Purity | 98% |
Target | HIV IN |
Target Protein | P03366 |
Solubility | >10.4mg/mL in DMSO |
Appearance | Solid |
Storage | Dry, dark and at 2 - 8 °C for six months or -20°C for two years. |
IC50 | EC50: 0.002 to 1.5 µ mol/L |
IUPAC Name | 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one |
InChI | InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m0/s1 |
InChIKey | XQSPYNMVSIKCOC-NTSWFWBYSA-N |
SMILES | C1[C@H](O[C@H](S1)CO)N2C=C(C(=NC2=O)N)F |