Emtricitabine S-Oxide (Mixture of Diastereomers)

• CAT Number: R051644
• CAS Number: 152128-77-3
• Molecular Formula: C₈H₁₀FN₃O₄S
• Molecular Weight: 263.25
• Purity: ≥95%
• Synonyms: 4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; [2R-(2α,5α)]-4-Amino-5-fluoro-1-[2-(hydroxymethyl)?-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone S-Oxide; [2R-(2α,5α)]-4-Amino-5-fluoro-1-?[2-(hydroxymethyl)-3-
• Target: HIV
• Storage: -20°C
• IUPAC Name: 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-3-oxo-1,3-oxathiolan-5-yl]pyrimidin-2-one
• InChI: InChI=1S/C8H10FN3O4S/c9-4-1-12(8(14)11-7(4)10)5-3-17(15)6(2-13)16-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+,17?/m0/s1
• InChIKey: DMOMZPWPIDCLMB-YGFFCSEESA-N
• SMILES: C1[C@H](O[C@H](S1=O)CO)N2C=C(C(=NC2=O)N)F

Emtricitabine S-Oxide (Mixture of Diastereomers)（Cat No.:R051644）is a derivative of emtricitabine, an antiretroviral nucleoside reverse transcriptase inhibitor (NRTI) used in HIV treatment. The S-oxide modification introduces diastereomers, making it a valuable tool for studying the metabolic pathways and oxidative transformations of emtricitabine. This compound aids in understanding drug stability, pharmacokinetics, and potential oxidative metabolites in antiretroviral therapies. Its role in research contributes to optimizing emtricitabine-based treatments and assessing the impact of structural modifications on antiviral efficacy and drug metabolism.