For research use only. Not for therapeutic Use.
Emzadirib (RAD51-IN-2) is a RAD51 inhibitor extracted from patent WO2019/051465A1[1].
Emzadirib exhibts an EC50 of ≤1 μM in activation-induced cytidine deaminase (AID) positive cells[1].
| Catalog Number | I019240 |
| CAS Number | 2301085-04-9 |
| Synonyms | propan-2-yl N-[3-(tert-butylsulfamoyl)-4-[2-[4-(propan-2-yloxycarbonylamino)cyclohexyl]-1,3-thiazol-5-yl]phenyl]carbamate |
| Molecular Formula | C27H40N4O6S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C27H40N4O6S2/c1-16(2)36-25(32)29-19-10-8-18(9-11-19)24-28-15-22(38-24)21-13-12-20(30-26(33)37-17(3)4)14-23(21)39(34,35)31-27(5,6)7/h12-19,31H,8-11H2,1-7H3,(H,29,32)(H,30,33) |
| InChIKey | OVXFEICGTUUFPE-UHFFFAOYSA-N |
| SMILES | CC(C)OC(=O)NC1CCC(CC1)C2=NC=C(S2)C3=C(C=C(C=C3)NC(=O)OC(C)C)S(=O)(=O)NC(C)(C)C |
| Reference | [1]. Alfredo C. Castro, et al. Rad51 inhibitors. WO2019/051465A1. |
