For research use only. Not for therapeutic Use.
Emzeltrectinib is a potent tyrosine kinase inhibitor with antineoplastic activity[1][2].
| Catalog Number | I041948 |
| CAS Number | 2223678-97-3 |
| Synonyms | 2-amino-5-[(2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide |
| Molecular Formula | C17H15F3N6O |
| Purity | ≥95% |
| InChI | InChI=1S/C17H15F3N6O/c18-8-1-2-11(20)10(5-8)12-6-9(19)7-25(12)13-3-4-26-17(23-13)14(16(22)27)15(21)24-26/h1-5,9,12H,6-7H2,(H2,21,24)(H2,22,27)/t9-,12+/m0/s1 |
| InChIKey | YFTARXQOKASKBW-JOYOIKCWSA-N |
| SMILES | C1C(CN(C1C2=C(C=CC(=C2)F)F)C3=NC4=C(C(=NN4C=C3)N)C(=O)N)F |
| Reference | [1]. Zhu Li, et al. Preparation of aminopyrazolopyrimidine compounds useful as neurotrophic factor tyrosine kinase receptor inhibitors: World Intellectual Property Organization, WO2018077246. 2018-05-03. [2]. WHO Drug Information-World Health Organization (WHO). |
