For research use only. Not for therapeutic Use.
EN523 is a OTUB1 recruiter. EN523 targets a non-catalytic allosteric cysteine C23 in the K48-ubiquitin-specific deubiquitinase OTUB1[1].
| Catalog Number | I044063 |
| CAS Number | 2094893-05-5 |
| Synonyms | 1-(5-methylfuran-2-yl)-4-prop-2-enoylpiperazin-2-one |
| Molecular Formula | C12H14N2O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C12H14N2O3/c1-3-10(15)13-6-7-14(11(16)8-13)12-5-4-9(2)17-12/h3-5H,1,6-8H2,2H3 |
| InChIKey | KYXPDOMFYBFXKO-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(O1)N2CCN(CC2=O)C(=O)C=C |
| Reference | [1]. Henning NJ, et al. Deubiquitinase-targeting chimeras for targeted protein stabilization. Nat Chem Biol. 2022;18(4):412-421. |
