1808714-73-9-EN6 EN6

EN6

For research use only. Not for therapeutic Use.

  • CAT Number: I018058
  • CAS Number: 1808714-73-9
  • Molecular Formula: C₁₉H₁₄F₂N₄O₂
  • Molecular Weight: 368.34
  • Purity: ≥95%
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EN6 (CAT: I018058) is a selective inhibitor of epidermal growth factor receptor (EGFR) signaling, specifically targeting the EGFR tyrosine kinase. It has been investigated for its potential to treat cancers where EGFR activation plays a key role in tumor growth and metastasis. EN6 works by disrupting EGFR-related signaling pathways, which can reduce cell proliferation and induce apoptosis in cancer cells. Research is ongoing to explore its effectiveness in overcoming resistance to current EGFR-targeted therapies, particularly in non-small cell lung cancer.


Catalog Number I018058
CAS Number 1808714-73-9
Molecular Formula C₁₉H₁₄F₂N₄O₂
Purity ≥95%
Target Autophagy
IUPAC Name 1-(2-fluorophenyl)-N-[4-fluoro-3-(prop-2-enoylamino)phenyl]pyrazole-4-carboxamide
InChI 1S/C19H14F2N4O2/c1-2-18(26)24-16-9-13(7-8-14(16)20)23-19(27)12-10-22-25(11-12)17-6-4-3-5-15(17)21/h2-11H,1H2,(H,23,27)(H,24,26)
InChIKey SUSXQEYPNDORDQ-UHFFFAOYSA-N
SMILES C=CC(=O)NC1=C(C=CC(=C1)NC(=O)C2=CN(N=C2)C3=CC=CC=C3F)F

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