For research use only. Not for therapeutic Use.
endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].<br>PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Catalog Number | I015330 |
CAS Number | 1263166-91-1 |
Molecular Formula | C₁₇H₁₇NO₅ |
Purity | ≥95% |
Target | PROTAC Linkers |
Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |