For research use only. Not for therapeutic Use.
Endosidin2 (ES2) binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. Endosidin2 inhibits exocytosis and endosomal recycling in both plant and human cells and enhances plant vacuolar trafficking. Endosidin2 is a valuable new tool for the study of exocytosis[1].
| Catalog Number | R067046 |
| CAS Number | 1839524-44-5 |
| Molecular Formula | C15H12FIN2O3 |
| Purity | ≥95% |
| Reference | [1]. Zhang C, et al. Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis. Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E41-50. |
