Enoxacin hydrate

• CAT Number: I005044
• CAS Number: 84294-96-2
• Molecular Formula: C15H17FN4O3 ● 1.5H2O
• Molecular Weight: 320.32
• Purity: ≥95%
• Target: antibacterial
• Solubility: DMSO:45mg/ml
• Storage: Keep in dark place,Inert atmosphere,Room temperature
• IUPAC Name: 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid;trihydrate
• InChI: InChI=1S/2C15H17FN4O3.3H2O/c2*1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20;;;/h2*7-8,17H,2-6H2,1H3,(H,22,23);3*1H2
• InChIKey: DKNNITGJCMPHKE-UHFFFAOYSA-N
• SMILES: CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNCC3)F)C(=O)O.CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNCC3)F)C(=O)O.O.O.O

Enoxacin（Cat No.:I005044） is a broad-spectrum antibacterial agent belonging to the class of 6-fluoronaphthyridinone antibiotics. It exhibits activity against a wide range of bacteria, including both Gram-positive and Gram-negative organisms. Enoxacin works by inhibiting the DNA gyrase enzyme, which is essential for bacterial DNA replication and repair. This mechanism of action contributes to its effectiveness in treating various bacterial infections. Enoxacin has been used clinically for the treatment of urinary tract infections, respiratory tract infections, and sexually transmitted diseases.

Reference

[1]. Chin, N.-X. and H.C. Neu, In vitro activity of enoxacin, a quinolone carboxylic acid, compared with those of norfloxacin, new beta-lactams, aminoglycosides, and trimethoprim. Antimicrobial agents and chemotherapy, 1983. 24(5): p. 754-763.
[2]. Wijnands, W., T. Vree, and C. Herwaarden, Enoxacin decreases the clearance of theophylline in man. British journal of clinical pharmacology, 1985. 20(6): p. 583-588.