Enpp-1-IN-12

• CAT Number: I043574
• CAS Number: 2631703-41-6
• Molecular Formula: C16H18N6O3S
• Molecular Weight: 374.42
• Purity: ≥95%
• Synonyms: 2-[(6-amino-1H-imidazo[4,5-c]pyridin-4-yl)sulfanyl]-N-(4-hydroxy-3-methoxyphenyl)butanamide
• IUPAC Name: 2-[(2-amino-7H-purin-6-yl)sulfanyl]-N-(4-hydroxy-3-methoxyphenyl)butanamide
• InChI: InChI=1S/C16H18N6O3S/c1-3-11(14(24)20-8-4-5-9(23)10(6-8)25-2)26-15-12-13(19-7-18-12)21-16(17)22-15/h4-7,11,23H,3H2,1-2H3,(H,20,24)(H3,17,18,19,21,22)
• InChIKey: ZDCMJGUVFRHQEH-UHFFFAOYSA-N
• SMILES: CCC(C(=O)NC1=CC(=C(C=C1)O)OC)SC2=NC(=NC3=C2NC=N3)N

Enpp-1-IN-12（Cat No.:I043574）is a small molecule inhibitor targeting the enzyme ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), which plays a role in regulating various biological processes, including mineralization and immune modulation. ENPP1 is involved in the hydrolysis of nucleotides and influences the activity of signaling molecules such as adenosine. By inhibiting ENPP1, Enpp-1-IN-12 aims to modulate these pathways, potentially offering therapeutic benefits in diseases related to abnormal mineralization, such as cardiovascular disease and certain cancers. Ongoing research is focused on determining its efficacy and safety in treating conditions linked to ENPP1 dysregulation.