Enpp-1-IN-14

• CAT Number: I042925
• CAS Number: 2687222-59-7
• Molecular Formula: C15H22ClN5O4S
• Molecular Weight: 403.88
• Purity: ≥95%
• Synonyms: 4-(6,7-dimethoxyquinazolin-4-yl)-1,4-diazepane-1-sulfonamide;hydrochloride
• InChI: InChI=1S/C15H21N5O4S.ClH/c1-23-13-8-11-12(9-14(13)24-2)17-10-18-15(11)19-4-3-5-20(7-6-19)25(16,21)22;/h8-10H,3-7H2,1-2H3,(H2,16,21,22);1H
• InChIKey: QUKMVZAYVWFICZ-UHFFFAOYSA-N
• SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)N3CCCN(CC3)S(=O)(=O)N)OC.Cl

Enpp-1-IN-14（Cat No.:I042925）is a small molecule inhibitor being studied for its potential to treat disorders related to the ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) enzyme. ENPP1 is involved in regulating the metabolism of inorganic pyrophosphate (PPi), a molecule that helps maintain bone mineralization and cartilage health. Dysregulation of ENPP1 activity can contribute to conditions such as generalized arterial calcification and skeletal diseases. Enpp-1-IN-14 works by selectively inhibiting ENPP1, potentially preventing abnormal calcification and improving bone health. It is currently being evaluated in preclinical studies for its therapeutic potential in mineralization-related diseases.