Enpp-1-IN-16

• CAT Number: I041167
• CAS Number: 2289739-47-3
• Molecular Formula: C23H32N4O4
• Molecular Weight: 428.52
• Purity: ≥95%
• Synonyms: tert-butyl 8-(6,7-dimethoxyquinazolin-4-yl)-2,8-diazaspiro[4.5]decane-2-carboxylate
• InChI: InChI=1S/C23H32N4O4/c1-22(2,3)31-21(28)27-11-8-23(14-27)6-9-26(10-7-23)20-16-12-18(29-4)19(30-5)13-17(16)24-15-25-20/h12-13,15H,6-11,14H2,1-5H3
• InChIKey: USKNLBGKOOFYMG-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC2(C1)CCN(CC2)C3=NC=NC4=CC(=C(C=C43)OC)OC

Enpp-1-IN-16（Cat No.:I041167）is a small molecule inhibitor targeting ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), an enzyme involved in hydrolyzing nucleotide sugars and regulating cellular signaling pathways related to phosphate metabolism and bone mineralization. ENPP1 has been implicated in various diseases, including osteoporosis, chronic kidney disease, and vascular calcification. By inhibiting ENPP1, Enpp-1-IN-16 may help modulate mineralization processes and reduce pathological calcification. This compound is being investigated for its potential therapeutic applications in conditions where dysregulated ENPP1 activity contributes to tissue calcification and bone disorders, offering a novel approach to treatment.