Enrofloxacin

For research use only. Not for therapeutic Use.

  • CAT Number: A000520
  • CAS Number: 93106-60-6
  • Molecular Formula: C19H22FN3O3
  • Molecular Weight: 359.40
  • Purity: ≥95%
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Enrofloxacin(Cat No.:A000520)is a broad-spectrum fluoroquinolone antibiotic commonly used in veterinary medicine. It targets bacterial DNA gyrase and topoisomerase IV, inhibiting bacterial DNA replication and transcription. Effective against a wide range of Gram-positive and Gram-negative bacteria, Enrofloxacin is primarily used to treat respiratory, urinary tract, and gastrointestinal infections in animals. It is also used for systemic and localized infections, especially in livestock and pets. Due to its pharmacokinetic properties, Enrofloxacin is often preferred for treating infections in animals, offering rapid absorption and long-lasting effects.


Catalog Number A000520
CAS Number 93106-60-6
Synonyms

93106-60-6; Baytril; Enrofloxacine; CFPQ; Enrofloxacino

Molecular Formula C19H22FN3O3
Purity ≥95%
Target Anti-infection
Storage -20°C
IUPAC Name 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxoquinoline-3-carboxylic acid
InChI InChI=1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)
InChIKey SPFYMRJSYKOXGV-UHFFFAOYSA-N
SMILES CCN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F
Reference

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PubMed PMID: 29128840.
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2: Kirby A, Lewbart GA, Hancock-Ronemus A, Papich MG. Pharmacokinetics of
enrofloxacin and ciprofloxacin in Atlantic horseshoe crabs (Limulus polyphemus)
after single injection. J Vet Pharmacol Ther. 2017 Oct 25. doi:
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3: Rico A, Zhao W, Gillissen F, Lürling M, Van den Brink PJ. Effects of
temperature, genetic variation and species competition on the sensitivity of
algae populations to the antibiotic enrofloxacin. Ecotoxicol Environ Saf. 2017
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PubMed PMID: 29055776.
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4: Roth N, Mayrhofer S, Gierus M, Weingut C, Schwarz C, Doupovec B, Berrios R,
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prevalence of antibiotic-resistant E. coli in cecum of broilers. Poult Sci. 2017
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overflows from animal lot and residential sewage lagoons and a receiving-stream.
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6: Li J, Hao H, Cheng G, Liu C, Ahmed S, Shabbir MAB, Hussain HI, Dai M, Yuan Z.
Microbial Shifts in the Intestinal Microbiota of Salmonella Infected Chickens in
Response to Enrofloxacin. Front Microbiol. 2017 Sep 8;8:1711. doi:
10.3389/fmicb.2017.01711. eCollection 2017. PubMed PMID: 28943868; PubMed Central
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7: Li J, Hao H, Cheng G, Wang X, Ahmed S, Shabbir MAB, Liu Z, Dai M, Yuan Z. The
effects of different enrofloxacin dosages on clinical efficacy and resistance
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8: Carrascosa A, Gutierrez L, De la Pe&#241;a A, Candanosa IE, Tapia G, Sumano H.
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Leptospirosis in a Hamster Model. Antimicrob Agents Chemother. 2017 Oct
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9: Pan M, Li S, Wang J, Sheng W, Wang S. Development and Validation of a
Reproducible and Label-Free Surface Plasmon Resonance Immunosensor for
Enrofloxacin Detection in Animal-Derived Foods. Sensors (Basel). 2017 Aug
30;17(9). pii: E1984. doi: 10.3390/s17091984. PubMed PMID: 28867795; PubMed
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10: Parpounas A, Litskas V, Hapeshi E, Michael C, Fatta-Kassinos D. Assessing the
presence of enrofloxacin and ciprofloxacin in piggery wastewater and their
adsorption behaviour onto solid materials, with a newly developed chromatographic
method. Environ Sci Pollut Res Int. 2017 Aug 25. doi: 10.1007/s11356-017-9849-9.
[Epub ahead of print] PubMed PMID: 28842853.

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