For research use only. Not for therapeutic Use.
Entacapone-d10 (CAS: 1185241-19-3), a premium pharmaceutical research compound designed for advanced studies in Parkinson’s disease and neuropharmacology. As a deuterated analog of Entacapone, it offers enhanced stability and improved pharmacokinetic properties. Entacapone-d10 is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel therapies for Parkinson’s disease. Trusted by leading laboratories, Entacapone-d10 is your go-to solution for cutting-edge neuropharmacological research. Unlock new possibilities in Parkinson’s treatment with Entacapone-d10, where innovation meets reliability.
| Catalog Number | S000132 |
| CAS Number | 1185241-19-3 |
| Molecular Formula | C14H5D10N3O5 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| IUPAC Name | (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-bis(1,1,2,2,2-pentadeuterioethyl)prop-2-enamide |
| InChI | InChI=1S/C14H15N3O5/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9/h5-7,18-19H,3-4H2,1-2H3/b10-5+/i1D3,2D3,3D2,4D2 |
| InChIKey | JRURYQJSLYLRLN-YFIMXNTNSA-N |
| SMILES | [2H]C([2H])([2H])C([2H])([2H])N(C(=O)/C(=C/C1=CC(=C(C(=C1)O)O)[N+](=O)[O-])/C#N)C([2H])([2H])C([2H])([2H])[2H] |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. E Nissinen, et al. Biochemical and pharmacological properties of a peripherally acting catechol-O-methyltransferase inhibitor entacapone. Naunyn Schmiedebergs Arch Pharmacol. 1992 Sep;346(3):262-6. [3]. Shiming Peng, et al. Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1. Sci Transl Med |
