For research use only. Not for therapeutic Use.
Entadamide A (compound 1) is a tryptophan derivative. Entadamide A prevents tryptophan depletion by inhibiting indoleamine 2, 3-dioxygenase (IDO), thereby inhibiting HIV replication. Entadamide A can be used in drug and neuropsychiatric studies of redesivir [1].
| Catalog Number | M000902 |
| CAS Number | 100477-88-1 |
| Synonyms | (E)-N-(2-hydroxyethyl)-3-methylsulfanylprop-2-enamide |
| Molecular Formula | C6H11NO2S |
| Purity | ≥95% |
| InChI | InChI=1S/C6H11NO2S/c1-10-5-2-6(9)7-3-4-8/h2,5,8H,3-4H2,1H3,(H,7,9)/b5-2+ |
| InChIKey | NBRCIHAGNJRRRI-GORDUTHDSA-N |
| SMILES | CSC=CC(=O)NCCO |
| Reference | [1]. Nzowa LK, et al. Two new tryptophan derivatives from the seed kernels of Entada rheedei: effects on cell viability and HIV infectivity. Fitoterapia. 2013 Jun;87:37-42. |
