EPI-7170

• CAT Number: I026919
• CAS Number: 2139288-26-7
• Molecular Formula: C22H28Cl3NO6S
• Molecular Weight: 540.88
• Purity: ≥95%
• Synonyms: N-[(2R)-3-[4-[2-[3,5-dichloro-4-[(2S)-3-chloro-2-hydroxypropoxy]phenyl]propan-2-yl]phenoxy]-2-hydroxypropyl]methanesulfonamide
• InChI: InChI=1S/C22H28Cl3NO6S/c1-22(2,15-8-19(24)21(20(25)9-15)32-12-16(27)10-23)14-4-6-18(7-5-14)31-13-17(28)11-26-33(3,29)30/h4-9,16-17,26-28H,10-13H2,1-3H3/t16-,17-/m1/s1
• InChIKey: DCXVYXPVNSMWPG-IAGOWNOFSA-N
• SMILES: CC(C)(C1=CC=C(C=C1)OC[C@@H](CNS(=O)(=O)C)O)C2=CC(=C(C(=C2)Cl)OC[C@@H](CCl)O)Cl

EPI-7170（Cat No.:I026919）is an experimental compound under investigation for its potential in treating cancer. It functions as a novel, selective inhibitor of the enzyme sphingosine kinase 2 (SK2), which is involved in regulating cell growth, survival, and inflammation. By inhibiting SK2, EPI-7170 aims to disrupt cancer cell proliferation and enhance the immune system’s ability to target tumors. Early preclinical studies suggest that EPI-7170 may be effective in treating a variety of cancers, particularly those resistant to conventional therapies. Clinical trials are underway to evaluate its safety and efficacy.