Epinephrine

For research use only. Not for therapeutic Use.

  • CAT Number: A000753
  • CAS Number: 51-43-4
  • Molecular Formula: C9H13NO3
  • Molecular Weight: 183.20
  • Purity: ≥95%
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Adrenaline (Cat No.:A000753), also known as adrenaline, is a naturally occurring catecholamine and hormone crucial for the body’s fight-or-flight response. It acts on alpha and beta adrenergic receptors, leading to increased heart rate, bronchodilation, vasoconstriction, and elevated blood glucose levels. Medically, epinephrine is used to treat anaphylaxis, cardiac arrest, asthma attacks, and severe allergic reactions. It is typically administered via injection or inhalation. Rapid-acting and lifesaving, epinephrine plays a vital role in emergency medicine and acute care interventions.


CAS Number 51-43-4
Synonyms

L-Adrenaline; Adrenaline; L-epinephrine; Adrenalin; Levoepinephrine

Molecular Formula C9H13NO3
Purity ≥95%
Target Adrenergic Receptor
Solubility Soluble in DMSO > 10 mM
Storage -20°C
InChI 1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1
InChIKey UCTWMZQNUQWSLP-VIFPVBQESA-N
SMILES CNCC(C1=CC(=C(C=C1)O)O)O
Reference

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SA, Olson M, Shekar KC, Rees JN, Carlson K, Sebastian P, McKnite S, Raveendran G,
Aufderheide TP, Yannopoulos D. Role of epinephrine and extracorporeal membrane
oxygenation in the management of ischemic refractory ventricular fibrillation: a
randomized trial in pigs. JACC Basic Transl Sci. 2017 Jun;2(3):244-253. doi:
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Central PMCID: PMC5693223.
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PubMed PMID: 29151840; PubMed Central PMCID: PMC5680749.
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3: Al-Noori S, Cimpan A, Maltzer Z, Kaiyala KJ, Ramsay DS. Plasma corticosterone,
epinephrine, and norepinephrine levels increase during administration of nitrous
oxide in rats. Stress. 2017 Nov 16:1-5. doi: 10.1080/10253890.2017.1402175. [Epub
ahead of print] PubMed PMID: 29145764.

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Allergy Diagnoses, Epinephrine Orders, and Epinephrine Administrations in New
York City Schools. J Pediatr. 2017 Nov;190:93-99. doi:
10.1016/j.jpeds.2017.07.038. PubMed PMID: 29144278.
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5: Dong W, Ren Y, Bai Z, Jiao J, Chen Y, Han B, Chen Q. Synthesis of
tetrahexahedral Au-Pd core-shell nanocrystals and reduction of graphene oxide for
the electrochemical detection of epinephrine. J Colloid Interface Sci. 2017 Oct
31;512:812-818. doi: 10.1016/j.jcis.2017.10.071. [Epub ahead of print] PubMed
PMID: 29121608.
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6: Liu JL, Zeng WN, Wang FY, Chen C, Gong XY, Yang H, Tan ZJ, Jia XL, Yang L.
Effects of low-dose epinephrine on perioperative hemostasis and inflammatory
reaction in major surgeries: a randomized clinical trial. J Thromb Haemost. 2017
Nov 6. doi: 10.1111/jth.13896. [Epub ahead of print] PubMed PMID: 29108091.
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Donati MB, de Gaetano G, Iacoviello L, Hoylaerts MF, Cerletti C. Neuromedin U
potentiates ADP- and epinephrine-induced human platelet activation. Thromb Res.
2017 Sep 29;159:100-108. doi: 10.1016/j.thromres.2017.09.027. [Epub ahead of
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8: Katz D, Hamburger J, Gutman D, Wang R, Lin HM, Marotta M, Zahn J, Beilin Y.
The Effect of Adding Subarachnoid Epinephrine to Hyperbaric Bupivacaine and
Morphine for Repeat Cesarean Delivery: A Double-Blind Prospective Randomized
Control Trial. Anesth Analg. 2017 Oct 26. doi: 10.1213/ANE.0000000000002542.
[Epub ahead of print] PubMed PMID: 29077615.

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9: Fukuda T, Kondo Y, Hayashida K, Sekiguchi H, Kukita I. Time to epinephrine and
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10: Smith N, Giordano K, Thompson A, DePiero A. Failure of Outpatient Management
With Different Observation Times After Racemic Epinephrine for Croup. Clin
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