Epinine

For research use only. Not for therapeutic Use.

  • CAT Number: M016502
  • CAS Number: 501-15-5
  • Molecular Formula: C9H13NO2
  • Molecular Weight: 167.208
  • Purity: ≥95%
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Epinine (Cat No.:M016502), also known as N-2-(3,4-dihydroxyphenyl)ethylmethylamine, is an impurity F of dopamine hydrochloride and can be used for control analysis.


Catalog Number M016502
CAS Number 501-15-5
Synonyms

4-(2-methylaminoethyl)pyrocatechol;N-2-(3,4-dihydroxyphenyl)ethylmethylamine;Deoxyepinephrine;4-[2-(methylamino)ethyl]-1,2-benzenediol;Epinine;N-Methyldopamine;4-[2-(methylamino)ethyl]benzene-1,2-diol

Molecular Formula C9H13NO2
Purity ≥95%
Storage -20°C
IUPAC Name 4-[2-(methylamino)ethyl]benzene-1,2-diol
InChI InChI=1S/C9H13NO2/c1-10-5-4-7-2-3-8(11)9(12)6-7/h2-3,6,10-12H,4-5H2,1H3
InChIKey NGKZFDYBISXGGS-UHFFFAOYSA-N
SMILES CNCCC1=CC(=C(C=C1)O)O
Reference

1: Lundberg B, Behndig A. The mydriatic effect of intracameral epinine
hydrochloride. Invest Ophthalmol Vis Sci. 2009 Nov;50(11):5336-8. doi:
10.1167/iovs.09-3651. Epub 2009 May 27. PubMed PMID: 19474400.

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2: Strolin Benedetti M, Sanson G, Bona L, Gallina M, Persiani S, Tipton KF. The
oxidation of dopamine and epinine by the two forms of monoamine oxidase from rat
liver. J Neural Transm Suppl. 1998;52:233-8. PubMed PMID: 9564622.
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3: Martínez-Mir I, Palop V, Morales-Olivas FJ, Esta&#241; L, Rubio E. The effects of
epinine on arterial blood pressure and regional vascular resistances in
anesthetized rats. Gen Pharmacol. 1998 Jul;31(1):75-9. PubMed PMID: 9595283.
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4: Di Napoli P, Di Crecchio A, Di Muzio M, Contegiacomo G, Spoletini L, Barsotti
A. [Endothelium-protective effects of epinine (N-methyldopamine) in myocardial
ischemia-reperfusion in the isolated working rat heart]. Cardiologia. 1997
Nov;42(11):1173-8. Italian. PubMed PMID: 9534310.
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5: Schwinger RH, Schulz C, Brixius K, B&#246;hm M, Müller-Ehmsen J, Erdmann E. Effect
of epinine on tension of human renal arteries. Naunyn Schmiedebergs Arch
Pharmacol. 1996 Aug-Sep;354(3):343-7. PubMed PMID: 8878065.

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6: Daul A, Elter-Schulz M, Poller U, Jockenh&#246;vel F, P&#246;nicke K, Boomsma F, Man
in/’t Veld AJ, Sch&#228;fes RF, Brodde OE. Dose-dependent separation of dopaminergic
and adrenergic effects of epinine in healthy volunteers. Naunyn Schmiedebergs
Arch Pharmacol. 1995 Oct;352(4):429-37. PubMed PMID: 8532072.
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7: Kajita M, Niwa T, Maruyama W, Nakahara D, Takeda N, Yoshizumi H, Tatematsu A,
Watanabe K, Naoi M, Nagatsu T. Endogenous synthesis of N-methylnorsalsolinol in
rat brain during in vivo microdialysis with epinine. J Chromatogr B Biomed Appl.
1994 Apr 1;654(2):263-9. PubMed PMID: 8044287.

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