For research use only. Not for therapeutic Use.
Epirizole (Mepirizole) is an orally active NSAID (nonsteroidal anti-inflammatory agent). Epirizole shows anti-inflammatory activity, and can be used in chronic rheumatoid arthritis research[1].
Epirizole (1-1000 μM; 24 h) increases MDR1 mRNA expression in Caco-2 cells[1].
| Catalog Number | M082069 |
| CAS Number | 18694-40-1 |
| Synonyms | 4-methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidine |
| Molecular Formula | C11H14N4O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C11H14N4O2/c1-7-5-9(16-3)13-11(12-7)15-10(17-4)6-8(2)14-15/h5-6H,1-4H3 |
| InChIKey | RHAXSHUQNIEUEY-UHFFFAOYSA-N |
| SMILES | CC1=CC(=NC(=N1)N2C(=CC(=N2)C)OC)OC |
| Reference | [1]. Takara K, et al. Effects of nonsteroidal anti-inflammatory drugs on the expression and function of P-glycoprotein/MDR1 in Caco-2 cells. Drug Chem Toxicol. 2009;32(4):332-7. |
