For research use only. Not for therapeutic Use.
Episyringaresinol 4′-O-β-D-glncopyranoside (compound 22), isolated from Alhagi sparsifolia Shap, is a natural potential neuroinflammatory inhibitor[1].
Episyringaresinol 4′-O-β-D-glncopyranoside inhibits NO production in LPS-induced N9 microglial cells dramatically in a dose independent manner with an IC50 of 91.50 μM.
| Catalog Number | I046099 |
| CAS Number | 137038-13-2 |
| Synonyms | (2S,3R,4S,5S,6R)-2-[4-[(3R,3aS,6R,6aS)-3-(4-hydroxy-3,5-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-2,6-dimethoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol |
| Molecular Formula | C28H36O13 |
| Purity | ≥95% |
| InChI | InChI=1S/C28H36O13/c1-34-16-5-12(6-17(35-2)21(16)30)25-14-10-39-26(15(14)11-38-25)13-7-18(36-3)27(19(8-13)37-4)41-28-24(33)23(32)22(31)20(9-29)40-28/h5-8,14-15,20,22-26,28-33H,9-11H2,1-4H3/t14-,15-,20-,22-,23+,24-,25+,26+,28+/m1/s1 |
| InChIKey | WEKCEGQSIIQPAQ-FKLBZQFOSA-N |
| SMILES | COC1=CC(=CC(=C1O)OC)C2C3COC(C3CO2)C4=CC(=C(C(=C4)OC)OC5C(C(C(C(O5)CO)O)O)O)OC |
| Reference | [1]. Zhou D, et al. Natural potential neuroinflammatory inhibitors from Alhagi sparsifolia Shap. Bioorg Med Chem Lett. 2017 Feb 15;27(4):973-978. |
