For research use only. Not for therapeutic Use.
Eplerenone（Cat No.:A000257）is a selective aldosterone receptor antagonist used primarily to treat hypertension and heart failure. By blocking the effects of aldosterone, it reduces sodium retention and water reabsorption, thereby lowering blood pressure and decreasing the strain on the heart. Eplerenone also prevents the remodeling of heart tissue post-myocardial infarction, improving cardiovascular outcomes. With a favorable side effect profile compared to other diuretics, it is well-tolerated and suitable for long-term use. Eplerenone enhances patient outcomes by effectively managing blood pressure and protecting against heart failure progression.
| Catalog Number | A000257 |
| CAS Number | 107724-20-9 |
| Synonyms | Epoxymexrenone; Inspra; 107724-20-9; Selara; SC-66110 |
| Molecular Formula | C24H30O6 |
| Purity | ≥95% |
| Target | Mineralocorticoid Receptor |
| Solubility | Limited solubility |
| Storage | -20°C |
| IUPAC Name | methyl (1R,2S,9R,10R,11S,14R,15S,17R)-2,15-dimethyl-5,5'-dioxospiro[18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-ene-14,2'-oxolane]-9-carboxylate |
| InChI | InChI=1S/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17-,19+,21+,22+,23-,24-/m1/s1 |
| InChIKey | JUKPWJGBANNWMW-VWBFHTRKSA-N |
| SMILES | CC12CCC(=O)C=C1CC(C3C24C(O4)CC5(C3CCC56CCC(=O)O6)C)C(=O)OC |
