ERK1/2 inhibitor 7

• CAT Number: I044087
• CAS Number: 2648455-13-2
• Molecular Formula: C23H22FN7OS
• Molecular Weight: 463.53
• Purity: ≥95%
• Synonyms: 5-[(3-fluorophenyl)methyl]-6,6-dimethyl-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyrrolo[3,4-d][1,3]thiazol-4-one
• InChI: InChI=1S/C23H22FN7OS/c1-13-11-25-22(27-16-8-9-26-30(16)4)29-17(13)20-28-18-19(33-20)23(2,3)31(21(18)32)12-14-6-5-7-15(24)10-14/h5-11H,12H2,1-4H3,(H,25,27,29)
• InChIKey: FJGLPZZZNWMMII-UHFFFAOYSA-N
• SMILES: CC1=CN=C(N=C1C2=NC3=C(S2)C(N(C3=O)CC4=CC(=CC=C4)F)(C)C)NC5=CC=NN5C

ERK1/2 inhibitor 7 is a potent ERK inhibitor with an IC50 of 0.94 nM for ERK2 (WO2021110168A1, WX006)[1].

Reference

[1]. WO2021110168A1.