For research use only. Not for therapeutic Use.
Erlotinib, Free Base (Cat.No:A000115) is a medication used for the treatment of non-small cell lung cancer and pancreatic cancer. It belongs to the class of tyrosine kinase inhibitors and works by inhibiting epidermal growth factor receptor (EGFR) activity. Erlotinib has shown effectiveness in slowing the progression of certain cancers and improving patient outcomes.
| Catalog Number | A000115 |
| CAS Number | 183321-74-6 |
| Synonyms | CP358774, NSC 718781 |
| Molecular Formula | C22H23N3O4 |
| Purity | ≥95% |
| Target | Protein Tyrosine Kinase/RTK |
| Solubility | >19.7mg/mL in DMSO |
| Storage | Store at -20°C |
| IUPAC Name | N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine |
| InChI | InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25) |
| InChIKey | AAKJLRGGTJKAMG-UHFFFAOYSA-N |
| SMILES | COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC |
