For research use only. Not for therapeutic Use.
Erythromycin Thiocyanate（Cat No.:I017985）is a derivative of erythromycin, a macrolide antibiotic effective against a variety of gram-positive bacteria and some gram-negative bacteria. It works by inhibiting bacterial protein synthesis, binding to the 50S ribosomal subunit, and preventing the growth and replication of bacteria. Erythromycin Thiocyanate is often used in pharmaceutical synthesis as an intermediate or precursor for other erythromycin-based compounds. Known for its stability and bioactivity, it serves as a valuable component in the development of macrolide antibiotics and research on bacterial resistance mechanisms in clinical microbiology.
| Catalog Number | I017985 |
| CAS Number | 7704-67-8 |
| Molecular Formula | C₃₈H₆₈N₂O₁₃S |
| Purity | ≥95% |
| Target | Cell Cycle/DNA Damage |
| IUPAC Name | (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione |
| InChI | InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1 |
| InChIKey | ULGZDMOVFRHVEP-RWJQBGPGSA-N |
| SMILES | CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O |
| Reference | [1]. Gribble MJ, et al. Erythromycin. Med Clin North Am. 1982 Jan;66(1):79-89.<br>[2]. Nakornchai S, et al. Activity of azithromycin or erythromycin in combination with antimalarial drugs against multidrug-resistant Plasmodium falciparum in vitro. Acta Trop. 2006 Dec;100(3):185-91. Epub 2006 Nov 28. |
