Erythronolide B

• CAT Number: R050124
• CAS Number: 3225-82-9
• PubChem Substance ID: 441113
• Molecular Formula: C21H38O7
• Molecular Weight: 402.528
• Purity: ≥95%
• IUPAC Name: (3R,4S,5S,6R,7R,9R,11R,12S,13R,14R)-14-ethyl-4,6,7,12-tetrahydroxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
• InChI: InChI=1S/C21H38O7/c1-8-15-11(3)17(23)12(4)16(22)10(2)9-21(7,27)19(25)13(5)18(24)14(6)20(26)28-15/h10-15,17-19,23-25,27H,8-9H2,1-7H3/t10-,11+,12+,13+,14-,15-,17+,18+,19-,21-/m1/s1
• InChIKey: ZFBRGCCVTUPRFQ-HWRKYNCUSA-N
• SMILES: CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)O)C)O)(C)O)C)C)O)C

Erythronolide B is a macrolide antibiotic precursor derived from the fermentation of the bacterium Saccharopolyspora erythraea. It serves as a key intermediate in the biosynthesis of erythromycin, a widely used antibiotic. Erythronolide B contains a 14-membered lactone ring and is essential for the antibacterial activity of erythromycin. Research on erythronolide B focuses on its biosynthetic pathways, potential modifications to enhance antibiotic properties, and its role in producing novel macrolide antibiotics to combat resistant bacterial strains.