Esmolol Hydrochloride

For research use only. Not for therapeutic Use.

  • CAT Number: A000886
  • CAS Number: 81161-17-3
  • Molecular Formula: C16H26ClNO4
  • Molecular Weight: 331.80
  • Purity: ≥95%
Inquiry Now

Esmolol Hydrochloride(Cat No.:A000886)is a short-acting, cardioselective beta-1 adrenergic receptor blocker used to manage acute arrhythmias, including supraventricular tachycardia and intraoperative hypertension. It works by reducing heart rate and myocardial contractility, making it effective in controlling rapid heart rhythms and reducing blood pressure during critical situations. Due to its rapid onset and short half-life, Esmolol Hydrochloride is ideal for use in emergency or surgical settings where immediate but easily reversible beta-blockade is required. It is administered intravenously and closely monitored for its quick yet controlled effects.


Catalog Number A000886
CAS Number 81161-17-3
Synonyms

Esmolol HCL; Brevibloc; 81161-17-3; ASL-8052; Asl 8052

Molecular Formula C16H26ClNO4
Purity ≥95%
Target Neuronal Signaling
Storage -20°C
IUPAC Name methyl 3-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoate;hydrochloride
InChI InChI=1S/C16H25NO4.ClH/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3;/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3;1H
InChIKey GEKNCWBANDDJJL-UHFFFAOYSA-N
SMILES CC(C)NCC(COC1=CC=C(C=C1)CCC(=O)OC)O.Cl
Reference

1: Zhao B, Sun W. Incompatibility of esmolol hydrochloride and furosemide in a
central venous access port. Am J Health Syst Pharm. 2014 Jun 1;71(11):901-2. doi:
10.2146/ajhp130526. PubMed PMID: 24830993.
<br>

2: Wiest DB, Garner SS, Childress LM. Stability of esmolol hydrochloride in 5%
dextrose injection. Am J Health Syst Pharm. 1995 Apr 1;52(7):716-8. PubMed PMID:
7627740.
<br>

3: Baaske DM, Dykstra SD, Wagenknecht DM, Karnatz NN. Stability of esmolol
hydrochloride in intravenous solutions. Am J Hosp Pharm. 1994 Nov
1;51(21):2693-6. PubMed PMID: 7856582.
<br>

4: Jordan D, Shulman SM, Miller ED Jr. Esmolol hydrochloride, sodium
nitroprusside, and isoflurane differ in their ability to alter peripheral
sympathetic responses. Anesth Analg. 1993 Aug;77(2):281-90. PubMed PMID: 8102224.
<br>

5: Vucevic M, Purdy GM, Ellis FR. Esmolol hydrochloride for management of the
cardiovascular stress responses to laryngoscopy and tracheal intubation. Br J
Anaesth. 1992 May;68(5):529-30. PubMed PMID: 1642945.
<br>

6: Schaaf LJ, Robinson DH, Vogel GJ, Wulf BG, Drda KD, Moses JO. Stability of
esmolol hydrochloride in the presence of aminophylline, bretylium tosylate,
heparin sodium, and procainamide hydrochloride. Am J Hosp Pharm. 1990
Jul;47(7):1567-71. PubMed PMID: 2368749.
<br>

7: Karnatz NN, Wong J, Baaske DM, Johnson JH, Speicher ER, Herbranson DE.
Stability of esmolol hydrochloride and sodium nitroprusside in intravenous
admixtures. Am J Hosp Pharm. 1989 Jan;46(1):101-4. PubMed PMID: 2565685.
<br>

8: Colucci RD, Cobuzzi LE, Halpern NA. Visual compatibility of esmolol
hydrochloride and various injectable drugs during simulated Y-site injection. Am
J Hosp Pharm. 1988 Mar;45(3):630-2. Erratum in: Am J Hosp Pharm 1988
Jun;45(6):1281. PubMed PMID: 2897164.
<br>

9: Karnatz NN, Wong J, Kesler H, Baaske DM, Speicher ER. Compatibility of esmolol
hydrochloride with morphine sulfate and fentanyl citrate during simulated Y-site
administration. Am J Hosp Pharm. 1988 Feb;45(2):368-71. PubMed PMID: 2896460.
<br>

10: Thompson DF, Thompson GD. Visual compatibility of esmolol hydrochloride and
furosemide in 5% dextrose or 0.9% sodium chloride injections. Am J Hosp Pharm.
1987 Dec;44(12):2740. PubMed PMID: 3434585.

Request a Quote