Esmolol

• CAT Number: I027016
• CAS Number: 81147-92-4
• Molecular Formula: C16H25NO4
• Molecular Weight: 295.379
• Purity: 98%
• Synonyms: Esmolol; (+-)-Esmolol; ASL 8052-001
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: Benzenepropanoic acid, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, methyl ester
• InChI: InChI=1S/C16H25NO4/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3
• InChIKey: AQNDDEOPVVGCPG-UHFFFAOYSA-N
• SMILES: O=C(OC)CCC1=CC=C(OCC(O)CNC(C)C)C=C1

Esmolol is a short acting hyperselective β-adrenergic blocker effective in blunting adrenergic response to several perioperative stimuli and so it might interfere in the effect of the anesthetic drugs on the brain. Esmolol is effective not only in attenuating intraoperative hemodynamic changes related to sympathetic overdrive but also in minimizing significant propofol and sevoflurane requirements without compromising the hemodynamic status.

Reference

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