Esomeprazole Magnesium trihydrate

• CAT Number: I002658
• CAS Number: 217087-09-7
• Molecular Formula: C34H42MgN6O9S2
• Molecular Weight: 767.17
• Purity: ≥95%
• Synonyms: magnesium;5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide;trihydrate
• Target: Proton Pump
• Solubility: DMSO 125 mg/ml; Water < 4 mg/ml
• Storage: Store at -20°C

Esomeprazole Magnesium trihydrate(CAT: I002658) is a proton pump inhibitor (PPI) drug that is used to treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcer disease, Zollinger-Ellison syndrome. It works by reducing the amount of acid produced in the stomach.

Reference

[1]. Sandstr?m M, Davidson G, Tolia V et al. Phase I, multicenter, randomized, open-label study evaluating the pharmacokinetics and safety profile of repeated once-daily doses of intravenous esomeprazole in children 0 to 17 years of age. Clin Ther. 2012 Aug;34(8):1828-38.

[2]. Wang-Smith L, Fort J, Zhang Y, Sostek M. Pharmacokinetics and relative bioavailability of a fixed-dose combination of enteric-coated naproxen and non-enteric-coated esomeprazole magnesium. J Clin Pharmacol. 2012 May;52(5):670-80.

[3]. Johnson TJ, Hedge DD. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9.

[4]. Esomeprazole