For research use only. Not for therapeutic Use.
Estrone 3-sulfate (CAS 438-67-5) is an endogenous steroid and an estrogen ester that is biologically inactive. It is converted by steroid sulfatase into estrone. Estrone 3-sulfate has been investigated as a ligand for targeting organic anion transporting polypeptides for the detection of hormone-dependent breast cancers.
| Catalog Number | R048714 |
| CAS Number | 438-67-5 |
| Synonyms | Estra-1,3,5(10)-trien-17-one 3-(Sulfooxy) Sodium Salt; Estrone Sulfate Sodium Salt; Conestoral; Estrone Sodium Sulfate; Morestin; NSC 18313; Sodium Estrone-3-sulfate; |
| Molecular Formula | C18H21O5S • Na |
| Purity | ≥95% |
| Target | Metabolic Enzyme/Protease |
| Storage | -20°C |
| IUPAC Name | sodium;[(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] sulfate |
| InChI | InChI=1S/C18H22O5S.Na/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);/q;+1/p-1/t14-,15-,16+,18+;/m1./s1 |
| InChIKey | VUCAHVBMSFIGAI-ZFINNJDLSA-M |
| SMILES | CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)OS(=O)(=O)[O-].[Na+] |
| Reference | <span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">1.Banerjee, Nilasha, et al. "Estrone-3-sulphate, a potential novel ligand for targeting breast cancers." <i style="font-family: Arial, sans-serif; font-size: 13px;">PloS one</i> 8.5 (2013): e64069.</span></span></span> |
