Estrone-d2-1

For research use only. Not for therapeutic Use.

  • CAT Number: S000863
  • CAS Number: 56588-58-0
  • Molecular Formula: C18H20D2O2
  • Molecular Weight: 272.38
  • Purity: ≥95%
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Estrone-d2-1(Cat No.:S000863)is a deuterated form of estrone, a naturally occurring estrogen steroid hormone. The “d2” notation indicates that two hydrogen atoms in the molecule have been replaced with deuterium (a stable isotope of hydrogen), which is commonly used in research for tracking and analytical purposes. Estrone itself is involved in the regulation of various physiological processes, including reproductive health, bone density, and cardiovascular function. Estrone-d2-1 is typically used in pharmacokinetic studies, metabolic research, and assays where isotopic labeling is necessary to trace hormone metabolism or interactions within biological systems.


Catalog Number S000863
CAS Number 56588-58-0
Molecular Formula C18H20D2O2
Purity ≥95%
IUPAC Name (8R,9S,13S,14S)-16,16-dideuterio-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-17-one
InChI InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1/i7D2
InChIKey DNXHEGUUPJUMQT-XIMAIENTSA-N
SMILES [2H]C1(C[C@H]2[C@@H]3CCC4=C([C@H]3CC[C@@]2(C1=O)C)C=CC(=C4)O)[2H]
Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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[2]. Caupos E, et al. Photodegradation of estrone enhanced by dissolved organic matter under simulated sunlight. Water Res. 2011;45(11):3341-3350.
[Content Brief]

[3]. de Padua Mansur A, et al. Long-term prospective study of the influence of estrone levels on events in postmenopausal women with or at high risk for coronary artery disease. ScientificWorldJournal. 2012;2012:363595.
[Content Brief]

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