Ethambutol (Cat No.: I004765) is an antimycobacterial compound that prevents cell wall formation by inhibiting the activity of arabinosyltransferase. This product has an anti-tuberculosis effect, and it still has an inhibitory effect on tuberculosis resistance to commonly used anti-tuberculosis drugs. Its antibacterial effect is weaker than that of isoniazid and similar to that of streptomycin. Ineffective against other bacteria and fungi.
| Catalog Number | I004765 |
| CAS Number | 74-55-5 |
| Synonyms | (2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol |
| Molecular Formula | C10H24N2O2 |
| Purity | ≥95% |
| Target | Antibiotic |
| Solubility | 10 mM in DMSO |
| Storage | 2-8°C |
| IUPAC Name | (2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol |
| InChI | InChI=1S/C10H24N2O2/c1-3-9(7-13)11-5-6-12-10(4-2)8-14/h9-14H,3-8H2,1-2H3/t9-,10-/m0/s1 |
| InChIKey | AEUTYOVWOVBAKS-UWVGGRQHSA-N |
| SMILES | CCC(CO)NCCNC(CC)CO |
| Reference | <p style=/line-height:25px/> <br>[2]. Rastogi, N., V. Labrousse, and K.S. Goh, In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages. Curr Microbiol, 1996. 33(3): p. 167-75. <br>[3]. Kaur, D. and G.K. Khuller, In vitro, ex-vivo and in vivo activities of ethambutol and sparfloxacin alone and in combination against mycobacteria. Int J Antimicrob Agents, 2001. 17(1): p. 51-5. </p> |
