For research use only. Not for therapeutic Use.
Ethaselen(CAT: I006726) is a selenium-containing small molecule that has shown potential as an anticancer agent. It works by modulating the activity of thioredoxin reductase (TrxR), an enzyme involved in regulating cellular redox balance. By inhibiting TrxR, Ethaselen induces oxidative stress in cancer cells, leading to apoptosis and cell death. This compound has been studied for its effectiveness in treating various cancers, including lung cancer, due to its ability to selectively target cancer cells while sparing normal cells. Ethaselen is of particular interest in cancer research, offering a promising approach for therapies that leverage oxidative stress to eliminate malignant cells.
| Catalog Number | I006726 |
| CAS Number | 217798-39-5 |
| Synonyms | Ethaselen; 1 2bis (12benzisoselenazolone3 (2H)ketone) ethane BBSKE.;2,2/’-(ethane-1,2-diyl)bis(benzo[d][1,2]selenazol-3(2H)-one) . |
| Molecular Formula | C16H12N2O2Se2 |
| Purity | ≥95% |
| Target | TrxR |
| Solubility | Soluble in DMSO, not in water |
| Storage | 0 - 4°C for short term or -20 °C for long term |
