Ethidium homodimer

For research use only. Not for therapeutic Use.

  • CAT Number: R072019
  • CAS Number: 61926-22-5
  • Molecular Formula: C46H50Cl4N8
  • Molecular Weight: 856.75
  • Purity: ≥95%
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Ethidium homodimer(Cat No.:R072019)is a fluorescent dye commonly used in molecular biology for detecting and quantifying DNA. It binds to double-stranded DNA, intercalating between the base pairs and emitting a strong red fluorescence when exposed to ultraviolet light. Due to its high affinity for nucleic acids, it is often used in DNA quantification, cell viability assays, and studies of apoptosis or DNA damage. Ethidium homodimer is particularly useful in identifying dead or compromised cells, as it can penetrate cell membranes that are damaged, making it a valuable tool in cellular and molecular research.


CAS Number 61926-22-5
Synonyms

5-[3-[2-[3-(3,8-diamino-6-phenylphenanthridin-5-ium-5-yl)propylamino]ethylamino]propyl]-6-phenylphenanthridin-5-ium-3,8-diamine;dichloride;dihydrochloride

Molecular Formula C46H50Cl4N8
Purity ≥95%
IUPAC Name 5-[3-[2-[3-(3,8-diamino-6-phenylphenanthridin-5-ium-5-yl)propylamino]ethylamino]propyl]-6-phenylphenanthridin-5-ium-3,8-diamine;dichloride;dihydrochloride
InChI InChI=1S/C46H46N8.4ClH/c47-33-13-17-37-39-19-15-35(49)29-43(39)53(45(41(37)27-33)31-9-3-1-4-10-31)25-7-21-51-23-24-52-22-8-26-54-44-30-36(50)16-20-40(44)38-18-14-34(48)28-42(38)46(54)32-11-5-2-6-12-32;;;;/h1-6,9-20,27-30,49-52H,7-8,21-26,47-48H2;4*1H
InChIKey ZKAJUKABUUJRLB-UHFFFAOYSA-N
SMILES C1=CC=C(C=C1)C2=C3C=C(C=CC3=C4C=CC(=CC4=[N+]2CCCNCCNCCC[N+]5=C6C=C(C=CC6=C7C=CC(=CC7=C5C8=CC=CC=C8)N)N)N)N.Cl.Cl.[Cl-].[Cl-]
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