For research use only. Not for therapeutic Use.
Ethopropazine (Isothazine) hydrochloride is a potent, selective BChE inhibitor and a poor AChE inhibitor. Ethopropazine hydrochloride is a phenothiazine compound with anticholinergic properties. Ethopropazine hydrochloride can be used for the research of Parkinson’s disease[1][2].
| Catalog Number | M069089 |
| CAS Number | 1094-08-2 |
| Synonyms | N,N-diethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride |
| Molecular Formula | C19H25ClN2S |
| Purity | ≥95% |
| InChI | InChI=1S/C19H24N2S.ClH/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21;/h6-13,15H,4-5,14H2,1-3H3;1H |
| InChIKey | VXPCQISYVPFYRK-UHFFFAOYSA-N |
| SMILES | CCN(CC)C(C)CN1C2=CC=CC=C2SC3=CC=CC=C31.Cl |
| Reference | [1]. Prabhu S, et al. Enhancement of dissolution of ethopropazine using solid dispersions prepared with phospholipid and/or polyethylene glycol. Drug Dev Ind Pharm. 2001 May;27(5):413-8. [2]. Reiner E, et al. Activity of cholinesterases in human whole blood measured with acetylthiocholine as substrate and ethopropazine as selective inhibitor of plasma butyrylcholinesterase. Arh Hig Rada Toksikol. 2004 Apr;55(1):1-4. |
