For research use only. Not for therapeutic Use.
Ethyl-3,4-dephostatin is a novel inhibitor of the interactions of CFTR-associated ligand and PSD-95/Dlg1/ZO-1 domain.
Catalog Number | I027085 |
CAS Number | 237756-11-5 |
Synonyms | Ethyl-3,4-dephostatin; ED; |
Molecular Formula | C8H10N2O3 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | N-(3,4-dihydroxyphenyl)-N-ethylnitrous amide |
InChI | InChI=1S/C8H10N2O3/c1-2-10(9-13)6-3-4-7(11)8(12)5-6/h3-5,11-12H,2H2,1H3 |
InChIKey | ZTXUSFPBLYQDDN-UHFFFAOYSA-N |
SMILES | O=NN(C1=CC=C(O)C(O)=C1)CC |
Reference | 1: Zhao Y, Cushing PR, Smithson DC, Pellegrini M, Pletnev AA, Al-Ayyoubi S, Grassetti AV, Gerber SA, Guy RK, Madden DR. Cysteine modifiers suggest an allosteric inhibitory site on the CAL PDZ domain. Biosci Rep. 2018 Jul 6;38(4):BSR20180231. doi: 10.1042/BSR20180231. Erratum in: Biosci Rep. 2018 Jun 5;: PMID: 29472314; PMCID: PMC6435542. |