For research use only. Not for therapeutic Use.
Etofibrate is a combination of niacin and clofibrate (Item No. <span class=/itemid/>10956</span>) that acts as a hypolipidemic agent. <em>In vivo</em>, etofibrate decreases plasma cholesterol and triglyceride concentrations and increases bile cholesterol content in rats. It also decreases thromboxane formation, platelet aggregation, and plasma viscosity and inhibits neointima formation in a carotid artery balloon injury rat model. Formulations containing etofibrate have been used to treat hyperlipidemia.
| Catalog Number | A000168 |
| CAS Number | 31637-97-5 |
| Synonyms | NA |
| Molecular Formula | C18H18ClNO5 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 2-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxyethyl pyridine-3-carboxylate |
| InChI | InChI=1S/C18H18ClNO5/c1-18(2,25-15-7-5-14(19)6-8-15)17(22)24-11-10-23-16(21)13-4-3-9-20-12-13/h3-9,12H,10-11H2,1-2H3 |
| InChIKey | XXRVYAFBUDSLJX-UHFFFAOYSA-N |
| SMILES | CC(C)(C(=O)OCCOC(=O)C1=CN=CC=C1)OC2=CC=C(C=C2)Cl |
