For research use only. Not for therapeutic Use.
Etofylline (7-(β-Hydroxyethyl)theophylline) is a N-7-substituted derivative of Theophylline. Etofylline is a bronchodilator which can be used for the research of asthma. Etofylline is also an anticholesteremic and reduces total cholesterol level in the blood[1][2].
| Catalog Number | I003883 |
| CAS Number | 519-37-9 |
| Synonyms | 7-(2-hydroxyethyl)-1,3-dimethylpurine-2,6-dione |
| Molecular Formula | C9H12N4O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C9H12N4O3/c1-11-7-6(8(15)12(2)9(11)16)13(3-4-14)5-10-7/h5,14H,3-4H2,1-2H3 |
| InChIKey | NWPRCRWQMGIBOT-UHFFFAOYSA-N |
| SMILES | CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCO |
| Reference | [1]. Siemon G, et, al. [The effect of fominoben and oxyethyltheophylline in combination on pulmonary function and pulmonary hemodynamics in chronic-obstructive diseases of the airways (author’s transl)]. Arzneimittelforschung. 1978;28(4):698-700. [2]. Ufkes JG, et, al. Efficacy of theophylline and its N-7-substituted derivatives in experimentally induced bronchial asthma in the guinea-pig. Arch Int Pharmacodyn Ther. 1981 Oct;253(2):301-14. |
